Nobel Medicine Prize for cancer research
Stockholm: Two immunologists, James Allison of the US and Tasuku Honjo of Japan, won the 2018 Nobel Medicine Prize for research that has revolutionised the treatment of cancer, the jury said Monday. The pair was honoured “for their discovery of cancer therapy by inhibition of negative immune regulation,” the Nobel Assembly said.
Stockholm: The announcement Monday of the Nobel Medicine Prize opens this year’s amputated awards season, with no Literature Prize for the first time in 70 years because of a #MeToo scandal.
Like every year, Nobel aficionados have speculated wildly about possible winners, given the number of worthy candidates in the fields of medicine, physics, chemistry, peace and economics.
The medicine prize committee at Stockholm’s Karolinska Institute is the first to reveal its choice of laureates. But its announcement risks being at least partially eclipsed by a Stockholm court’s verdict around the same time against Frenchman Jean-Claude Arnault, charged with rape.
His close ties to the Swedish Academy, which awards the Nobel Literature Prize, have caused a scandal and deep rift in the Academy, prompting it to postpone this year’s prize for a year.
It is the first time the prize has been postponed since William Faulkner’s 1949 honour was awarded in 1950.
Without the Literature Prize this year, the most highly-anticipated award will be that for peace, announced on Friday in Oslo.
But before that come the science prizes, traditionally dominated by men working at US institutions.
Swedish public radio SR tipped however the medicine prize could go to two women for the gene-editing technique known as the CRISPR-Cas9 DNA snipping tool, a type of genetic “scissors” used to cut out a mutated gene in a human embryo and replace it by a corrected version.
However, the discovery could be too early for a Nobel, with a recent study suggesting the technique may damage DNA more than previously thought. A legal dispute is also raging over who discovered the technique.
It has been claimed on the one hand by the French-American research duo of Emmanuelle Charpentier and Jennifer Doudna, and on the other by Chinese-born American Feng Zhang.
Other research mentioned as Nobel-worthy include the cochlear implant, which can help deaf people to hear again, and gene sequencing, already honoured with a chemistry Nobel in 1980 but a field whose vast progress has revolutionised medical, biological and evolutionary research since then.
Swedish daily Svenska Dagbladet meanwhile cited research on opiates and pain relief, new blood vessel growth, and the creation of a giant gene and genome database as other possible award-winning fields. The physics prize will follow on Tuesday.
SR suggested the Royal Swedish Academy of Sciences could give the nod to research on zero dimensional quantum dots – very small semiconductor particles that play a key role in data communications, light diodes, solar cells and medical imaging.
Svenska Dagbladet, meanwhile, said the discovery of the so-called “spin Hall effect” in semiconductors could be honoured, or pioneering methods to determine the age, size and distance between galaxies.
Work on the mechanisms behind super-capacitators, a type of battery that can store large amounts of electricity, was also seen as a possibility.
The chemistry prize, to be announced Wednesday, could meanwhile go to recurring favourite John Goodenough, a 96-year old electrochemist whose work led to the invention of rechargeable lithium ion battery present in cell phones, computers and electric cars, SR said.
For the Peace Prize, the only Nobel announced in Oslo, there are 329 candidates this year but their names are kept secret.