New Delhi: India is the biggest manufacturer of hydroxychloroquine, the anti-malarial drug that is being touted as ‘game-changer’ in the fight against COVID-19 and is being aggressively sought by US President Donald Trump.
India has the capacity to quickly ramp up the output of hydroxychloroquine.
Days after it added the drug to the list of more than two dozen APIs that cannot be exported while officials get a handle on how much will be needed for COVID-19 outbreak in the country, India on Tuesday agreed to lift the ban after Trump sought supplies for the US.
India manufactures 70 per cent of the world’s supply of hydroxychloroquine, according to Indian Pharmaceutical Alliance (IPA) secretary-general Sudarshan Jain.
The country has a production capacity of 40 tonnes of hydroxychloroquine (HCQ) every month, implying 20 crore tablets of 200 mg each. And since the drug is also used to auto-immune diseases like rheumatoid arthritis and lupus, manufacturers have good production capacities that can also be ramped up.
Ipca Laboratories, Zydus Cadila and Wallace Pharmaceuticals are top pharma companies manufacturing HCQ in India.
Jain says the production capacity is sufficient to meet the current demand and if the need arises, the companies are committed to ramping up production.
Recently, the Ministry of Health and Family Welfare had reportedly placed an order for around 10 crore tables of HCQ with Ipca laboratories and Zydus Cadila.
The drug is not manufactured in developed nations such as the US because of non-existent malaria.
Hydroxychloroquine is very similar to chloroquine, one of the oldest and best-known anti-malarial drugs, but with lesser side-effects. It can be bought over the counter and fairly inexpensive.
But its purchase and use has been severely restricted as it was selectively used in the treatment of coronavirus because of its antiviral properties.
India gets the active pharmaceutical ingredient (API) that is used to manufacture HCQ from China and supplies so far have been steady.
As much as 70 per cent of all the APIs needed by India to manufacture drugs come from China.
After Trump stated that the US could “retaliate” if India does not release stocks of the drug, Indian officials said exports of hydroxychloroquine and paracetamol will be allowed depending on availability of stock after meeting domestic requirements and existing orders.
Last month, the US Food and Drug Administration (FDA) partially lifted a three-year-old ‘import alert’ on Ipca’s two plants to import the medicine. Zydus Cadila has also received an order from the US.
Pharma industry officials said the country has enough stock of HCQ and companies were ready to ramp up the capacity to meet domestic requirements as well as exports.
PTI